Mar 19, 2024



Promethazine DM Syrup for Cough and Cold Relief

Promethazine DM Syrup

Always seek advice from your healthcare provider before starting any new medication regimen. 

Introduction to Promethazine DM Syrup

Promethazine DM syrup is a widely used medication for temporarily relieving coughs and upper respiratory symptoms associated with allergies or the common cold. It is suitable for adults and children aged 2 years and older.

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What is Promethazine DM Syrup Used For?

The syrup is effectively used for:

  • Alleviating short-term coughs due to minor throat and bronchial irritation.

  • Easing upper respiratory symptoms, including runny nose and sneezing, primarily caused by allergies or the common cold.

How Does Promethazine DM Syrup Work?

This combination medication contains:

  • Promethazine: A phenothiazine that reduces allergy symptoms by blocking certain chemicals in the body.

  • Dextromethorphan: A cough suppressant that acts on the brain to reduce the urge to cough.

Understanding Side Effects and Precautions

While effective, Promethazine DM can cause side effects such as drowsiness, dizziness, and stomach upset. Serious side effects include neuroleptic malignant syndrome and severe breathing problems, especially in children under 2 years of age, which is why it's contraindicated for this age group.

Pharmacist Tips for Using Promethazine DM Syrup

  • Avoid combining with MAOIs or alcohol.

  • Not recommended for those with asthma or breathing problems.

  • Be cautious with other dextromethorphan-containing products to prevent overdose.

  • Consider sun protection, as Promethazine can increase sun sensitivity.

  • Consult your healthcare provider before using if pregnant or nursing.


Promethazine DM syrup provides effective relief from cough and cold symptoms but must be used cautiously due to its potential side effects and contraindications. Always consult healthcare professionals before beginning treatment, especially for children and pregnant women. In managing medication costs, consider exploring discount cards, like CareCard, that might be available to make your treatment more affordable.

Remember, while Promethazine DM syrup can alleviate symptoms, it does not cure the underlying cause of the cold or allergy, and should not be used long-term without a doctor's guidance. Always follow the dosage instructions carefully to ensure safe and effective use.

FAQs about Promethazine DM Syrup

How quickly does Promethazine DM syrup start working?

Typically, it begins to relieve symptoms within 20 to 30 minutes of ingestion.

Can Promethazine DM make me sleepy?

Yes, one of the most common side effects is drowsiness.

Is Promethazine DM syrup suitable for seniors?

Seniors should use caution and consult with healthcare providers due to increased sensitivity to side effects.

Can I use Promethazine DM syrup during pregnancy?

Consult with a healthcare provider, as Promethazine DM may not be safe during pregnancy.

What is the difference between Promethazine and Promethazine DM syrup?

Promethazine DM contains an additional cough suppressant, dextromethorphan, unlike standard Promethazine, which does not.

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Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. Prescription savings may vary by prescription and by pharmacy, and in some cases may be discounted up to 85% off cash price*. Please note, this is NOT insurance. CareCard offers you the opportunity to find prescription discount prices, which ultimately depend on the provider. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted rates. CareCard Inc. is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. This information is not mean to be a substitute for professional medical advice, treatment, or diagnosis. For additional information, please reach our customer support at 1-866-410-1217, Mon- Friday 9am – 5pm Est or email us at By using the CareCard prescription discount card or service, you are agreeing to CareCard’s Terms of Service.

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