Feb 15, 2023




Can You Take Mucinex and Sudafed Together?

Taking Medication

If you've ever been hit with an upper respiratory infection, like a cold or the flu, you know endless options are available over-the-counter (OTC) to help relieve symptoms. 

Mucinex and Sudafed are two OTC medications often used to treat symptoms such as chest congestion, nasal congestion, and sinus pressure. 

But can you take Mucinex and Sudafed together? Let's take a look at what these drugs are and if they can safely be used together. 

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What is Mucinex?

Mucinex (guaifenesin) is an expectorant, or a type of cough medicine, that helps reduce chest congestion by loosening mucus in your airways. 

Side effects of Mucinex

Although Mucinex is available OTC, it still has potential side effects, such as:

  • Constipation

  • Dizziness

  • Fatigue

  • Headache

  • Nausea and vomiting

What is Sudafed?

Sudafed (pseudoephedrine) is a decongestant that works by narrowing the blood vessels in your nose to reduce swelling and make it easier for you to breathe.

While you don't need a prescription for Sudafed, the FDA requires all products that contain pseudoephedrine to be sold from behind the pharmacy counter as it can be used to make an illegal drug called meth (methamphetamine). 

Side effects of Sudafed:

Common side effects of Sudafed include:

  • Sleep issues, like insomnia

  • Nausea and vomiting

  • Headache

  • Nervousness 

  • Restlessness

Rare, more severe side effects may also possibly occur. You should seek medical attention right away if you experience the following: 

  • An allergic reaction 

  • Dizziness

  • Stomach pain

  • Irregular heartbeat

  • Issues breathing 

Can You Take The Medications Together? 

Because both medications offer different types of relief, taking them together as directed is generally considered safe. 

Combination forms of Mucinex, such as Mucinex-D, contain pseudoephedrine. Therefore they shouldn't be taken with Sudafed or any other cough/cold medications, as they could lead to double dosing and dangerous side effects such as high blood pressure or increased heart rate. Speak to your pharmacist if you need help picking out the right medicine. 

It's also important to pay attention to how much of each medication you use. Taking too much Mucinex may cause nausea and vomiting, while taking too much Sudafed could cause dizziness or headache. 

In addition, both drugs should not be used for more than seven days unless otherwise directed by your doctor.  

Final thoughts

Together and separately, Mucinex and Sudafed can help manage your upper respiratory infection symptoms. However, it's important to remember that neither medicine treats bacterial infections like strep throat and certain sinus infections

You should see your healthcare provider as soon as possible if symptoms get worse or show no improvement, as this may indicate a bacterial infection, which would require antibiotics.

At CareCard, we are passionate about helping make your prescription payments more affordable, saving you up to 85% on prescription drugs and medications. You can search for an antibiotic medication coupon here and learn how CareCard can help make your medication payments more manageable.

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Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. Prescription savings may vary by prescription and by pharmacy, and in some cases may be discounted up to 85% off cash price*. Please note, this is NOT insurance. CareCard offers you the opportunity to find prescription discount prices, which ultimately depend on the provider. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted rates. CareCard Inc. is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. This information is not mean to be a substitute for professional medical advice, treatment, or diagnosis. For additional information, please reach our customer support at 1-866-410-1217, Mon- Friday 9am – 5pm Est or email us at hello@carecard.com. By using the CareCard prescription discount card or service, you are agreeing to CareCard’s Terms of Service.

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